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Do not give this medication to anyone elseeven if they have the same symptoms as you doIt can be harmful for people to take this medication if their doctor has not prescribed it.
Tolbutamide’s conversion to inactive metabolites has been shown to be catalyzed by xanthine oxidase from rat liverThe clinical significanceif anyof these observations is unknown.
Renal failure in association with administration of Zyloprim has been observed among patients with hyperuricemia secondary to neoplastic diseasesConcurrent conditions such as multiple myeloma and congestive myocardial disease were present among those patients whose renal dysfunction increased after Zyloprim was begunRenal failure is also frequently associated with gouty nephropathy and rarely with hypersensitivity reactions associated with ZyloprimAlbuminuria has been observed among patients who developed clinical gout following chronic glomerulonephritis and chronic pyelonephritis.
Laboratory TestsThe correct dosage and schedule for maintaining the serum uric acid within the normal range is best determined by using the serum uric acid as an index.
Stop using Zyloprim and call your doctor at once if you have a serious side effect such as:
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the dose of zyloprim allopurinol recommended for management of recurrent calcium oxalate stones in hyperuricosuric patients is 200 to 300 mg day in divided doses or as the single equivalent.